ResearchResearch paperComputer Vision · Multimodal Models · Efficiency & Inference1 source · Oct 19, 2026

XGLASS: X-Ray, Gaze and Language Assisted Slice Sequencing for CT Volumes

To enable such a prioritization, we propose XGLASS, a method that transfers medical expertise from 2D X-rays to 3D CT for task-aware slice prioritization.

Key points

  • Vision-language models (VLMs) achieve remarkable performance on 2D medical images, such as X-rays or pathology images, while 3D VLMs that directly process CT/MRI volumes lag behind due to limited 3D training data and the predominance of 2D foundation architectures.
  • To leverage powerful 2D VLMs for analyzing medical volumes, which contain hundreds of slices, it is therefore necessary to focus only on those few slices, which are diagnostically relevant.
  • XGLASS uses disease-conditioned importance maps derived from language-aligned radiologist gaze on X-rays and spatially aligns them with coronal CT projections, bringing gaze priors and CT content into a shared 2D representation.
  • The fused gaze-prior/CT projection is then used to predict a disease-specific ordering of axial slices, prioritizing diagnostically relevant slices.

Sources (1)

  • [1]XGLASS: X-Ray, Gaze and Language Assisted Slice Sequencing for CT Volumes
    arXiv (AI, ML, NLP, CV, robotics, multi-agent) · Oct 19, 12:13 PM
    To enable such a prioritization, we propose XGLASS, a method that transfers medical expertise from 2D X-rays to 3D CT for task-aware slice prioritization.
    Vision-language models (VLMs) achieve remarkable performance on 2D medical images, such as X-rays or pathology images, while 3D VLMs that directly process CT/MRI volumes lag behind due to limited 3D training data and the predominance of 2D foundation architectures.

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