ResearchResearch paperInterpretability1 source · Oct 20, 2026

IECG: Weakly-Supervised Interpretability-Enhancing Foundation Model for Electrocardiogram

We present IECG, a weakly-supervised ECG foundation model that jointly performs diagnostic classification and abnormality localization without requiring manual abnormal region annotations, overcoming a long-standing bottleneck in interpretable ECG learning.

Key points

  • Electrocardiography (ECG) is a cornerstone of cardiac diagnosis, yet most machine learning methods for ECG analysis lack interpretability, limiting their clinical adoption.
  • Central to IECG is a weakly-supervised attention strategy that explicitly incorporates clinical priors by deriving abnormality heatmap pseudo-labels from established ECG clinical knowledge.
  • During pretraining, IECG is jointly optimized with clinically guided attention supervision, ECG-text contrastive alignment, and report captioning objectives, enabling it to learn rich multimodal representations while producing localized waveform evidence.
  • Extensive experiments demonstrate that IECG achieves state-of-the-art abnormal region localization while maintaining strong classification performance, advancing trustworthy foundation models for ECG analysis.

Sources (1)

  • [1]IECG: Weakly-Supervised Interpretability-Enhancing Foundation Model for Electrocardiogram
    arXiv (AI, ML, NLP, CV, robotics, multi-agent) · Oct 20, 12:03 PM
    We present IECG, a weakly-supervised ECG foundation model that jointly performs diagnostic classification and abnormality localization without requiring manual abnormal region annotations, overcoming a long-standing bottleneck in interpretable ECG learning.
    Electrocardiography (ECG) is a cornerstone of cardiac diagnosis, yet most machine learning methods for ECG analysis lack interpretability, limiting their clinical adoption.

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