ResearchResearch paperLarge Language Models1 source · Oct 6, 2026

Language-model ratings of depression reflect the rater more than the patient

Language models promise tireless, consistent assessment, but can accurate raters disagree about individuals?

Key points

  • Depression has no diagnostic blood test.
  • We pre-registered 880 language-model raters, crossing 11 open models with prompting and scoring choices, and applied them to 189 interviews against the eight-item Patient Health Questionnaire.
  • Model choice explained 30.0% of summed-symptom score variance, stable participant differences 10.5%.
  • Two randomly drawn raters with area under the receiver operating characteristic curve (AUC) >= 0.70 disagreed on screening decisions for 40% of participants, on average.

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