ResearchResearch paperLarge Language Models1 source · Oct 12, 2026

PatientWM: Towards Generalizable Clinical World Models via Unified Patient States

To tackle these limitations, we propose PatientWM, a clinical world-model framework built around a unified patient state and sequential latent history.

Key points

  • Clinical decisions depend on anticipating how a patient's condition will evolve as treatment is adjusted and new evidence becomes available.
  • Existing medical world models capture patient-state evolution, but often define the evolving state around a particular modality or task, limiting reuse as inputs or prediction targets change.
  • Availability-aware encoders integrate observations available at each decision time into the patient state, while typed decoders produce task-specific clinical readouts without defining the state around any single target.
  • PatientWM further conditions each next-state prediction on the current state and supplied action together with a bounded, ordered history of preceding latent patient states and clinical actions, preserving recent treatment and response context.

Sources (1)

  • [1]PatientWM: Towards Generalizable Clinical World Models via Unified Patient States
    arXiv (AI, ML, NLP, CV, robotics, multi-agent) · Oct 12, 04:26 PM
    To tackle these limitations, we propose PatientWM, a clinical world-model framework built around a unified patient state and sequential latent history.
    Clinical decisions depend on anticipating how a patient's condition will evolve as treatment is adjusted and new evidence becomes available.

Extractive summary: sentences quoted from the sources.

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