ResearchResearch paperInterpretability · Large Language Models · Computer Vision1 source · Oct 15, 2026

MedPAO-VL: Interpretable and Protocol-Compliant Agent for Structured Radiology Report Generation

We present MedPAO-VL, a multimodal agent that shifts the paradigm from monolithic generation to explainable, iterative, protocol-compliant structured report generation.

Key points

  • Despite the remarkable generalization capabilities of Large Language Models, generating clinically accurate and structured radiology reports from medical images remains a significant challenge.
  • Unlike deterministic models, our plan-act-observe loop functions as a goal-oriented agent: it first perceives the Chest X-Ray through an explainable vision module designed to capture inherent diagnostic uncertainty, then iteratively refines the generated report by observing semantic discrepancies and self-correcting its generation for better alignment with visually detected clinical findings.
  • Evaluation of our framework demonstrates that this agentic reasoning improves clinical correctness and completeness, achieving an expert-rated accuracy score of 3.5/5 and a structural score of 4.3/5.
  • By prioritizing pathology specific explainability and iterative refinement over opaque end-to-end mapping, MedPAO-VL offers a transparent and clinically viable alternative for automated structured radiology report generation.

Sources (1)

  • [1]MedPAO-VL: Interpretable and Protocol-Compliant Agent for Structured Radiology Report Generation
    arXiv (AI, ML, NLP, CV, robotics, multi-agent) · Oct 15, 12:46 PM
    We present MedPAO-VL, a multimodal agent that shifts the paradigm from monolithic generation to explainable, iterative, protocol-compliant structured report generation.
    Despite the remarkable generalization capabilities of Large Language Models, generating clinically accurate and structured radiology reports from medical images remains a significant challenge.

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