ResearchResearch paperApplications1 source · Oct 16, 2026

Indirect Influences of Artificial Intelligence Advice on Complex Sepsis Treatment Decisions

Sepsis is a major public health concern, and many sepsis patients die due to ineffective hemodynamic management.

Key points

  • Artificial intelligence could support hemodynamic decisions, particularly in complex cases where conflicting information and comorbidities drive uncertainty and practice variation.
  • However, these systems' real-world value depends on not just accuracy, but how they influence the quality of clinician decisions.
  • We first retrospectively evaluated an AI system's recommendations in 6,928 sepsis patients, finding that they improved upon the original providers' decisions overall but had significantly worse performance in complex cases.
  • Our findings suggest that improving sepsis care decisions with AI may require accounting for these indirect influences resulting from human-AI collaborative reasoning.

Sources (1)

Extractive summary: sentences quoted from the sources.

Related