ResearchResearch paperComputer Vision1 source · Oct 12, 2026

MID: Mask-Image Distributional Divergence for Evaluating Medical Image Segmentation

We introduce MID (Mask-Image Distributional Divergence), a distribution-level evaluation metric for medical image segmentation.

Key points

  • Current evaluation protocols for medical image segmentation remain largely anchored in sample-wise comparisons, e.g., Dice and Hausdorff distance, which require each prediction to be paired with a ground-truth mask.
  • MID builds upon the observation that segmentation quality is a property of the joint image-mask distribution: a mask may be anatomically plausible in isolation yet incorrect for the image it accompanies.
  • MID compares the joint distribution of images and masks between a reference set and a set of predictions, without requiring sample-wise correspondence.
  • MID also detects distributional shifts across modalities and anatomies, identifies image-mask misalignment through controlled shuffling experiments, and produces reliable model rankings across real segmentation models.

Sources (1)

  • [1]MID: Mask-Image Distributional Divergence for Evaluating Medical Image Segmentation
    arXiv (AI, ML, NLP, CV, robotics, multi-agent) · Oct 12, 08:12 PM
    We introduce MID (Mask-Image Distributional Divergence), a distribution-level evaluation metric for medical image segmentation.
    Current evaluation protocols for medical image segmentation remain largely anchored in sample-wise comparisons, e.g., Dice and Hausdorff distance, which require each prediction to be paired with a ground-truth mask.

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